Molecule of the Month
CSTX-13 is a component of the venom of the spider Cupiennius salei, which enhances the neurotoxic activity of the main venom component CSTX-1. In contrast to CSTX-1, CSTX-13 is a two-chain peptide with two interchain and two intrachain disulphide bridges, consisting of 78 amino acids. Amino acid sequence and disulphide-bridge pattern have been elucidated in our laboratories.
This work was carried out in the group of Prof. Johann Schaller.