Molecule of the Month
February 2011

The conversion of alkylboranes to the corresponding alkanes is classically performed via protonolysis of alkylboranes. This simple reaction requires the use of severe reaction conditions, i.e. treatment with a carboxylic acid at high temperature (>150 C). We have recently developed a mild radical procedure for the transformation of organoboranes to alkanes where 4-tert-butylcatechol, a well-established radical inhibitor and antioxidant, is acting as a source of hydrogen atom.

This work was carried out in the group of Prof. Philippe Renaud.


  • G. Villa, G. Povie and P. Renaud;
    "Radical Chain Reduction of Alkylboron Compounds with Catechols"
    J. Am. Chem. Soc., 133, 59135920, (2011); doi:10.1021/ja110224d.