Molecule of the Month September 2013 |
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First Total Synthesis of Aignopsanoic Acid A | ||
The aignopsanes, a new class of sesquiterpenes, have been isolated in 2009 from the Indo Pacific marine sponge Cacospongia mycofijiensis. A member of this family, aignopsanoic acid A, could be prepared in seven steps starting from the easily available Wieland-Miescher ketone. This total synthesis has been carried out by Cédric Bürki in the group of Prof. Philippe Renaud in collaboration with the group of Prof. Josep Bonjoch (Universitat de Barcelona). References:
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