Understanding the challenges and opportunities of photobiocatalytic systems is essential for advancing sustainable and efficient chemical processes. This study presents the development of a dual-functionalized resin for photobiocatalysis, integrating an organic photocatalyst and the enzyme chloroperoxidase (CiVCPO).
The resin employs a porous emulsion-templated polymer (PolyHIPE) capable of generating hydrogen peroxide in situ under visible light irradiation. The immobilized enzyme catalyzes bromination reactions in a continuous flow system. This setup offers benefits such as enhanced operational stability, scalability, and improved light penetration, demonstrating its effectiveness through the bromination of aromatic substrates, including rutin, a natural flavonoid.

This research was conducted in the group of Prof. Dr. Francesca Paradisi.

References:

• E. Broumidis, F. Paradisi;
  "Engineering a Dual-Functionalized PolyHIPE Resin for Photobiocatalytic Flow Chemistry"
  Angew. Chem. Int. Ed., 2024, 63(21), e202401912/1-7; doi:10.1002/anie.202401912.